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. 2018 Feb 27;9:29. doi: 10.3389/fneur.2018.00029

Table 3.

Comparison of the classification of medx system and the truth as a multiclass problem for the six most prevalent diagnoses.

Truth (expert opinion)
Phobic postural vertigo MD VM BPPV BVP DBN VN Other cerebellar disorders Others Sensitivity (%) Specificity (%) PPV (%) NPV (%) Accuracy (%)
Test result (medx system) Phobic postural vertigo 95 1 2 1 1 2 1 0 15 80.5 82.5 52.5 94.6 82.1
MD 9 84 4 3 3 0 2 0 3 77.8 97.6 87.5 95.3 94.1
VM 49 8 35 2 0 0 1 0 6 34.7 97.8 76.1 88.3 87.4
BPPV 5 0 0 58 1 1 2 1 26 61.7 98.3 86.6 93.4 92.6
BVP 4 0 0 0 40 1 0 3 1 81.6 97.1 71.4 98.4 95.9
DBN 7 1 1 0 1 32 0 3 1 69.6 97.7 71.1 97.5 95.6
VN 2 2 1 2 2 1 11 0 5 42.3 99.0 64.7 97.5 96.6
Other cerebellar disorders 3 0 2 0 3 5 0 12 1 46.2 98.8 63.2 97.6 96.6
Others 7 0 1 1 5 3 0 0 25 59.5 89.8 30.1 96.8 87.7

Benign paroxysmal positional vertigo, benign paroxysmal positional vertigo; BVP, bilateral vestibulopathy; DBN, downbeat nystagmus syndrome; MD, Menière’s disease; VM, vestibular migraine; VN, vestibular neuritis. Other cerebellar disorders: cerebellar ataxia with neuropathy and bilateral vestibular areflexia syndrome; cerebellar ataxia; episodic ataxia type 2. Others: all other diagnoses (vestibular paroxysmia; multiple system atrophy; vestibular schwannoma, perilymph fistula; progressive supranuclear palsy; brainstem stroke). Sensitivity: true positive rate, specificity: true negative rate. PPV, positive predictive value; NPV, negative predictive value.