Table 4.

ROC Analyses for the optimal urine NNAL cut point using different urine cotinine criteria for active smoking.

Positive Cotinine Cutoff	AUC	Cutpoint	Noted For	Sensitivity	Specificity	Youden
		Volume Based - NNAL pg/ml
Cotinine > 10 ng/ml	0.917	6.2	Equality	0.872	0.873	0.743
		6.6	Youden	0.872	0.886	0.758
Cotinine > 15 ng/ml	0.942	8.2	Equality	0.884	0.884	0.768
		15.5	Youden	0.841	0.949	0.790
Cotinine > 20 ng/ml	0.955	13.9	Equality	0.931	0.931	0.862
		15.5	Youden	0.931	0.941	0.872
Cotinine > 30 ng/ml	0.971	14.4	Equality, Youden	0.946	0.934	0.882
		Creatinine Adjusted - NNAL (pg/mg creatinine)
Cotinine > 10 ng/ml	0.929	4.1	Equality	0.870	0.870	0.740
		5.6	Youden	0.857	0.917	0.774
Cotinine > 15 ng/ml	0.960	5.7	Equality	0.912	0.911	0.822
		6.6	Youden	0.912	0.924	0.836
Cotinine > 20 ng/ml	0.971	8.5	Equality	0.93	0.921	0.851
		6.6	Youden	0.965	0.908	0.873
Cotinine > 30 ng/ml	0.972	10.2	Equality	0.926	0.927	0.853
		6.6	Youden	0.981	0.904	0.885