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. Author manuscript; available in PMC: 2019 Mar 15.
Published in final edited form as: Neuroscience. 2018 Feb 2;374:13–24. doi: 10.1016/j.neuroscience.2018.01.031

Figure 3. Effects of neonatal ethanol exposure and choline treatments on morphometric parameters of apical dendrites of CA1 pyramidal neurons in PD9 male pups.

Figure 3

Morphometric measurements of apical dendrites of CA1 pyramidal neurons from male PD9 rats exposed to 5 g/Kg/day ethanol and/or 100 mg/Kg/day choline between PD4 and PD9 were analyzed by Neurolucida Explorer. A: Apical dendrite complexity (1,000×); a composite measurement defined as [(sum of terminal orders + number of ends)*(total dendrite length/number of primary dendrites)]. B: Apical dendrite length (in μm). C: Apical dendrite sum of terminal orders (defined as the number of “sister” branches encountered from each end to the cell body). D: Number of ends per apical dendrite. Shown in each graph is the mean ± the standard error from 48 neurons per condition. Multilevel analysis was carried out on original (C, D) or log-transformed (A, B) data. On data shown in B, C, and D we employed multiple comparison corrections using the Benjamini-Hochberg approach to adjust nominal p-values to FDR. +p<0.05; *q<0.05 (after FDR correction).