Table 3.
MB-loaded Ace-DEX MPs | OVA-loaded Ace-DEX MPs | EMPs | |||||
---|---|---|---|---|---|---|---|
Ace-DEX CAC (%) | 20 | 40 | 60 | 20 | 40 | 60 | 40 |
Compound EE (%) | 98.5 | 92.9 | 99.9 | 79.4 | 70.2 | 99.8 | - |
Compound Loading (μg agent/mg MP) | 9.85 | 9.29 | 9.99 | 7.94 | 7.02 | 9.98 | - |
Mean Diameter (nm) | 604 ± 43.6 | 539 ± 60.9 | 617 ± 59.1 | 552 ± 96.7 | 527 ± 110 | 557 ± 65.3 | 558 ± 74.2 |
Endotoxin level (EU/mL) | 0.047 | 0.063 | 0.038 | 0.027 | 0.044 | 0.081 | 0.059 |