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. 2018 Jan 8;2018:6067096. doi: 10.1155/2018/6067096

Figure 5.

Figure 5

Influences of ion channels on APs in hiPSC-CMs. APs were recorded at 1 Hz. Specific ion channel blockers or activators were applied to assess the contribution of an ion channel to AP. Percentage changes induced by drugs were calculated as (V drug − V control)/V control∗100, where V control is the value before the application of a drug and V drug is the value in the presence of a drug. (a) Percent (%) changes of resting potential (RP). (b) % changes of AP amplitude (APA). (c) % changes of maximal depolarization speed (V max). (d) % changes of APD at 50% repolarization (APD50). (e) % changes of APD at 90% repolarization (APD90). Values given are mean ± SEM. The number of cells (numbers in parentheses) is indicated in (b). ∗ p < 0.05 versus control.