Table 2.

Molecules differentially expressed by monocytes or IMs from animals or patients with COPD compared to healthy controls.

Molecule family	Encoded proteins	References
Cytokines	TNF-α ↓, IL-6 ↑	[146, 245]
Chemokines	CCL2 ↑, IL-8 ↓	[146, 252]
Chemokine receptors	CCR2 ↑	[253]
Metalloproteinases	MMP-9 ↓, Mmp-12 ↑	[146, 251]
Antigen presentation molecules	CD86 ↓	[252]
Integrins, PRRs	CD11b ↓, CD14 ↓, CD54 ↓	[146, 252]
MicroRNAs	miR-24-3p ↑, miR-93-5p ↑, miR-320a ↑, miR-320b ↑, miR1273g-3p ↓	[254]