Table 2.
Age- and gender-specific levels for urinary 8-oxodGsn/crea and 8-oxoGsn/crea (μmol/mol) derived from 1,228 normal subjects.
Age | |||||||||
---|---|---|---|---|---|---|---|---|---|
1–10 years | 11–20 years | 21–30 years | 31–40 years | 41–50 years | 51–60 years | 61–70 years | 71–80 years | 81–90 years | |
8-oxodGsn | |||||||||
Male | 2.01 ± 0.75 | 1.23 ± 0.52 | 1.30 ± 0.49 | 1.20 ± 0.48 | 1.23 ± 0.50 | 1.53 ± 0.61*,a,b | 1.79 ± 0.88*,a,b | 1.85 ± 0.92a | 1.91 ± 0.89a |
Female | 1.91 ± 0.76 | 1.54 ± 0.62 | 1.31 ± 0.53 | 1.35 ± 0.67 | 1.33 ± 0.74 | 1.88 ± 0.79b | 2.18 ± 0.96a,b | 2.16 ± 1.10a | 2.42 ± 0.83a |
8-oxoGsn | |||||||||
Male | 4.76 ± 1.45 | 1.48 ± 0.61 | 1.62 ± 0.40 | 1.70 ± 0.50 | 1.90 ± 0.54a | 2.1 ± 0.77*,a,b | 2.15 ± 0.66*,a | 2.62 ± 0.89*,b | 3.12 ± 1.2a,b |
Female | 5.05 ± 1.79 | 1.44 ± 0.40 | 1.53 ± 0.44 | 1.60 ± 0.50 | 1.76 ± 0.67b | 2.3 ± 0.60b | 2.88 ± 0.88a,b | 2.99 ± 0.80a | 2.9 ± 0.81a |
p < 0.05compared to age matched female group.
p < 0.05 compared with gender matched 11–20 years group.
p < 0.05 compared with the gender matched neighboring younger group.