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The difference in RMSF of EGFR upon binding to the ligands shown for dEGFR minus dEGFREGF (black curve), dEGFRNAG minus dEGFRNAG-EGF (red curve), and mEGFRNAG minus mEGFRNAG-EGF (blue curve). Zero line in bold black is shown for reference. A positive value indicates a decrease in RMSF upon addition of the ligand to the simulated EGFR. Monomers 1 and 2 are shown by the same line style for the dimeric EGFR systems.
