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. Author manuscript; available in PMC: 2019 Mar 1.

Published in final edited form as: Brain Res Bull. 2017 Nov 7;137:23–34. doi: 10.1016/j.brainresbull.2017.11.002

Table 1.

ACTH AUC Responses to PHYSO and SAL Following SCOP, PIREN, METHO, and SAL Pretreatment in Male and Female Rats^*

Treatment Group	Males ACTH AUC (pg/ml x min)	Females ACTH AUC (pg/ml x min)
SAL + SAL	144 ± 191	410 ± 126
SAL + PHYSO	1016 ± 268^a ^c	309 ± 175^a

SCOP 0.3 + PHYSO	6088 ± 1052^a ^c ^d	4138 ± 754^a ^c ^d
SCOP 0.3 + SAL	2132 ± 587^c	2130 ± 627^c ^d

PIREN 10 + PHYSO	1675 ± 684^c	2222 ± 777^c ^d
PIREN 30 + PHYSO	4308 ± 995^a ^c ^d	2336 ± 1016^a ^c ^d
PIREN 70 + PHYSO	9025 ± 1487^a ^c ^d	4655 ± 1479^a ^c ^d
PIREN 10 + SAL	584 ± 320	1268 ± 559

METHO 0.3 + PHYSO	1029 ± 283^c	689 ± 467
METHO 1 + PHYSO	373 ± 450	278 ± 273
METHO 3 + PHYSO	730 ± 614^a	−333 ± 1385^a
METHO 1 + SAL	312 ± 471	247 ± 220

^*

AUCs presented as mean ± SEM.

^a

sex difference at indicated dose (p < 0.05);

^c

vs. SAL + SAL (p < 0.05);

^d

vs. SAL + PHYSO (p < 0.05).