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. Author manuscript; available in PMC: 2019 Mar 1.

Published in final edited form as: Brain Res Bull. 2017 Nov 7;137:23–34. doi: 10.1016/j.brainresbull.2017.11.002

Table 2.

CORT AUC Responses to PHYSO and SAL Following SCOP, PIREN, METHO, and SAL Pretreatment in Male and Female Rats^*

Treatment Group	Males CORT AUC (ng/ml x min)	Females CORT AUC (ng/ml x min)
SAL + SAL	2551 ± 1355^a	7174 ± 1733^a
SAL + PHYSO	10710 ± 2045^c	12686 ± 3707^c

SCOP 0.3 + PHYSO	12889 ± 1696^a ^c	22602 ± 1773^a ^c ^d
SCOP 0.3 + SAL	10336 ± 1739^a ^c	19757 ± 2407^a ^c ^d

PIREN 10 + PHYSO	10153 ± 1359^a ^c	14678 ± 3076^a ^c
PIREN 30 + PHYSO	16545 ± 1451^a ^c ^d	22364 ± 3749^a ^c ^d
PIREN 70 + PHYSO	23502 ± 2421^a ^c ^d	28444 ± 2682^a ^c ^d
PIREN 10 + SAL	6878 ± 1270^a	15760 ± 3663^a ^c

METHO 0.3 + PHYSO	9908 ± 2272^c	11132 ± 4064
METHO 1 + PHYSO	5898 ± 1087	5031 ± 2130^d
METHO 3 + PHYSO	13246 ± 1754^a ^c	20975 ± 2663^a ^c ^d
METHO 1 + SAL	411 ± 1744^a ^d	11472 ± 3424^a

^*

AUCs presented as mean ± SEM.

^a

sex difference at indicated dose (p < 0.05);

^c

vs. SAL + SAL (p < 0.05);

^d

vs. SAL + PHYSO (p < 0.05).