Fig. 3.

(A1) various doses of NAC affect on the DNA fragmentation in uterine cells of female rat treated with arsenic. Lane distribution Lane 1: Control; Lane 2: Arsenic; Lane 3: Arsenic + NAC 50; Lane 4: Arsenic + NAC 100. (A2) The band intensity of DNA at its different positions on the agarose gel is evaluated by Image (J) software, expressed in relative/normalized values, and plotted on a graph. Picture shows that arsenic-induced severe DNA damage is prevented by the different doses of NAC exposure. (B) Arrows show Comet formation in uterine horn cells following arsenic ingestion. Arsenic-induced severe DNA breakage which was noticed in single cell apoptotic damage was noticeably prevented by both the doses of NAC. Panel distribution; B1: Control, B2: Arsenic, B3: Arsenic + NAC 50, B4: Arsenic + NAC 100.