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. 2018 Feb 13;5:278–287. doi: 10.1016/j.toxrep.2018.02.003

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© 2018 Published by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 4 — (A and B) Uterine and ovarian tissue were implanted in paraffin, serially sectioned laterally at 5 μM stained with eosin and hematoxylin (Harris) and observed under a microscope (magnification 340) to study the uterine (A) and ovarian (B) histo-architecture. The arrows show atretic follicles in ovary of arsenic treated rats.

Pictures showed the remarkable loss of secretory cells of uterine tissue along with distortion of endometrial layer. The numbers of atretic follicles were increased in the arsenic exposed group. Different doses of NAC co-treatment significantly secured such arsenic-induced uterine and ovarian disorders. Panel distribution; B1: Control, B2: Arsenic, B3: Arsenic + NAC 50, B4: Arsenic + NAC 100.