. 2018 Feb 13;5:278–287. doi: 10.1016/j.toxrep.2018.02.003

Table 3.

The protective effect of both the doses of NAC against arsenic was shown on the ovarian 17β-HSD activity and serum estradiol. In arsenic group the activity of this steroidogenic enzyme and the hormone level were diminished in contrast to the vehicle treated control group. NAC of different doses restored this arsenic-mediated alteration of enzyme activity and hormone level. Data represent mean ± SE, N = 6, ANOVA followed by post hoc Dunnett t-test, *p < 0.05, **p < 0.01, ***p < 0.001.

	Control	As³⁺	As³⁺ + NAC 50	As³⁺+ NAC 100
17 β-HSD (unit/mg of tissue/hr)	38.41 ± 9.5	2.32 ± 0.62**	12.90 ± 3.0*	25.72 ± 7.0
Estradiol (ng/ml)	28.06 ± 0.48	9.32 ± 0.38***	12.66 ± 0.57***	13.11 ± 0.56**