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. 2018 Feb 28;9:109. doi: 10.3389/fneur.2018.00109

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Copyright © 2018 Erga, Dalen, Ushakova, Chung, Tzoulis, Tysnes, Alves, Pedersen and Maple-Grødem.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Results of regularized regression with elastic net penalization for α-values between 0 and 1. Polymorphisms positively associated with ICDs (i.e., increases risk) are highlighted with red, while polymorphisms negatively associated with ICDs (i.e., decreases risk) are highlighted in blue, with the intensity of color reflecting the strength of association. Polymorphisms not associated with ICDs are white. Identified polymorphisms demonstrate significant association across all levels of α.