Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A schematic representation showing the mechanism of action of acrylamide (AA) in thyroid tumor in rats. Exposure to AA reduces serum T3 and T4, which stimulate hypothalamus of hypothalamus-pituitary-thyroid axis to secrete thyrotropin-releasing hormone (TRH). TRH stimulates pituitary gland to release thyroid-stimulating hormone (TSH), which subsequently stimulate thyroid gland to initiate proliferation of cells and eventually development of thyroid tumor.
