Table 1.

The summary of the histopathological results of rats repeatedly inhaled with sodium metabisulfite (SM).

Organ/histopathology	Group	Control	Low	Middle	High
	Dose (mg/m3)	0	5	20	100
	No. examined	4	4	4	4
Liver
No specific lesion		1 (25.0)	1 (25.0)	1 (25.0)	0 (0.00)
Cell infiltration, mononuclear or mixed		2 (50.0)	3 (75.0)	2 (50.0)	3 (75.0)
Grades: minimal		2	3	2	3
Cell infiltration, lymphocytic, portal		1 (25.0)	1 (25.0)	0 (0.00)	1 (25.0)
Grades: minimal		1	1	0	0
mild		0	0	0	1
Bile duct hyperplasia, focal		0 (0.00)	1 (25.0)	0 (0.00)	0 (0.00)
Grades: minimal		0	1	0	0
Steatosis, diffuse		0 (0.00)	0 (0.00)	1 (25.0)	1 (25.0)
Grades: minimal		0	0	1	1
Lung
No specific lesion		4 (100)	4 (100)	4 (100)	3 (75.0)
Arterial wall mineralization, focal		0 (0.00)	0 (0.00)	0 (0.00)	1 (25.0)
Grades: minimal		0	0	0	1