Table 2.
The summary of the histopathological results of rats repeatedly inhaled with the mixture of SM and propylene glycol (PG).
Groups histopathology | Groups | Control | Vehicle | Low | Middle | High |
---|---|---|---|---|---|---|
0 | PG1% | PG1%+SM1% | PG1%+SM5% | PG1%+SM20% | ||
No. examined | 4 | 4 | 4 | 4 | 4 | |
Liver | ||||||
No specific lesion | 1 (25.0) | 1 (25.0) | 1 (25.0) | 2 (50.0) | 0 (0.00) | |
Cell infiltration, mononuclear cells, | 3 (75.0) | 3 (75.0) | 3 (75.0) | 2 (50.0) | 4 (100) | |
multifocal | ||||||
Grades; minimal | 3 | 3 | 2 | 2 | 4 | |
mild | 0 | 0 | 1 | 0 | 0 | |
Lung | ||||||
No specific lesion | 3 (75.0) | 2 (50.0) | 3 (75.0) | 3 (75.0) | 3 (75.0) | |
Vascular mineralization, focal | 1 (25.0) | 1 (25.0) | 1 (25.0) | 0 (0.00) | 1 (25.0) | |
Grades; minimal | 1 | 1 | 1 | 0 | 1 | |
Nasal cavity | ||||||
No specific lesion | 4 (100) | 4 (100) | 4 (100) | 3 (75.0) | 0 (0.00) | |
Metaplasia, squamous cells, Line I | 0 (0.00) | 0 (0.00) | 0 (0.00) | 1 (25.0) | 4 (100) | |
Grades; minimal | 0 | 0 | 0 | 1 | 0 | |
mild | 0 | 0 | 0 | 0 | 4 |