Table 4.

Linear model analysis using different dopamine scores.

Dopamine score	AIC	Parameter estimate	p value
5-gene score	200.621	1·897	0.010
4-gene score without DRD1	202.871	1·785	0.030
4-gene score without DRD2	201.554	2·269	0.016
4-gene score without DRD3	198.989	2·306	0.005
4-gene score without COMT	202.270	1·906	0.023
4-gene score without DAT	202.568	2·121	0.026
DRD1 only	204.568	4·650	0.070
DRD2 only	205.621	2·946	0.122
DRD3 only	208.455	0·343	0.858
COMT only	205.722	3·710	0.128
DAT only	204.096	3·630	0.056

The dependent variable was the change in AHA-units from baseline to after the intervention. Various dopamine gene scores were used as explanatory variables together with age, sex, and BDNF gene score. Dopamine four-gene scores were formed by removing each single-gene contribution, and the contribution of each gene was calculated by using only that single gene in the model. The table shows the Akaike Information Criteria (AIC) for each model (lower values correspond to a better model), coefficient estimates for the dopamine score variables, and corresponding p-values.