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. 2018 Jan 31;28:274–286. doi: 10.1016/j.ebiom.2018.01.024

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© 2018 Published by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 5 — Effect of increasing inflammation in the eye on myopia progression. (a) The RE was determined as the difference in diopter measurements taken before and after treatment with 10 ng/mL TNF-α or IL-6 for 21 days. ANOVA was used to determine significant differences (p < 0.001), and Tukey's multiple comparisons tests were used for paired comparisons between PBS and TNF-α or IL-6-treated eyes. P < 0.05 was considered statistically significant. (b) The axial length was determined as the difference in axial length measurements taken before and after treatment with 10 ng/mL TNF-α or IL-6 for 21 days. An ANOVA was used to determine significant differences (p = 0.0043), and Tukey's multiple comparisons tests were used for paired comparisons between PBS and TNF-α or IL-6-treated eyes. P < 0.05 was considered statistically significant.