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. 2018 Jan 19;15(4):291–299. doi: 10.7150/ijms.22495

Figure 1.

Figure 1

Morphological changes of the DF during root development of DI3 of miniature pig. (A, A') H&E staining of DI3 at stage of E90; the boxed region in A was magnified in A'. The dental follicle (DF) was located outside of outer enamel epithelium (OEE) and beneath the dental papilla (DP) (boxed regions). HERS grew apically and directed root formation. (B, B') H&E staining of DI3 at the stage of PN10; the boxed region in B was magnified in B'. The DF was shaped like a crescent and was located between the apical foramen (AF) and the alveolar bone. The lateral coronal corner of DF (boxed region) was the area of differentiation from DF to periodontium. Periodontal ligament (PDL), cementum, broken HERS, dentin, and odontoblasts could be identified. Scale bars represent 100μm (A, A', B, B').