Table 4.

Bone turnover status and in-hospital outcomes

Outcomes	Bone turnover status
	Subtype 2B			Subtype 3			Subtype 4A			Subtype 4B
	OR	95%CI	P Value	OR	95%CI	P Value	OR	95%CI	P Value	OR	95%CI	P Value
cTnI rise	0.97	0.49-1.92	0.934	2.05	1.36-3.09	0.001	1.13	0.77-1.68	0.535	2.17	1.44-3.26	<0.001
	0.80	0.38-1.68	0.561	1.40	0.90-2.19	0.139	0.84	0.55-1.30	0.440	1.38	0.88-2.17	0.162
LOS>10days	1.08	0.57-2.04	0.891	1.54	1.03-2.28	0.034	2.20	1.54-3.15	<0.001	2.08	1.41-3.06	<0.001
	0.95	0.49-1.84	0.876	1.16	0.76-1.76	0.496	2.18	1.48-3.20	<0.001	1.74	1.17-2.61	0.007
LOS>20days	0.88	0.36-2.17	0.783	1.65	0.99-2.75	0.058	2.49	1.57-3.96	<0.001	1.54	0.92-2.56	0.098
	0.80	0.32-2.01	0.640	1.30	0.76-2.23	0.333	2.61	1.60-4.26	<0.001	1.40	0.82-2.36	0.209
CRP>100mg/L	1.74	0.92-3.29	0.088	2.40	1.59-3.63	<0.001	1.23	0.87-1.74	0.238	1.30	0.88-1.91	0.184
	1.67	0.81-3.43	0.165	1.75	1.12-2.72	0.013	0.97	0.66-1.42	0.883	0.94	0.61-1.44	0.778
CRP>150mg/L	1.24	0.68-2.26	0.483	1.70	1.16-2.49	0.006	1.28	0.91- 1.81	0.156	1.49	1.02-2.17	0.038
	1.18	0.62-2.24	0.622	1.44	0.96-2.15	0.078	1.04	0.72-1.52	0.821	1.20	0.80-1.78	0.374
New RCF d/c	1.31	0.31-5.50	0.709	1.26	0.47-3.42	0.649	1.09	0.42-2.83	0.858	1.36	0.50-3.68	0.858
	0.85	0.17-4.30	0.847	1.18	0.38-3.67	0.781	1.09	0.41-2.89	0.857	1.48	0.47-4.66	0.507

Multivariate regression comparisons with subtypes1and 2A combined.

Model 1 (1^st line): adjustment for age and gender. Model 2 (2^nd line): included chronic heart failure, dementia, chronic kidney disease (GFR<60ml/min/1.73m²), history of malignancy, PTH>6.8pmol/L, albumin<33 g/L, anaemia (haemoglobin <120g/L), hip or any non-vertebral fracture, use of osteoporotic treatment, age and gender.

Abbreviations: OR, odds ratio; CI, confidence interval; cTnI, cardiac troponin I; LOS, length of hospital stay; CRP, C-reactive protein; RCF d/c, new discharges to a permanent residential care facility.