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Expression of osteoblast genes (RUNX-2, ALP and Col-I) treated for 24 h with zoledronate, alendronate or clodronate at doses of 10-5, 10-7, or 10-9 M. MG-63 cell line (A,B,C); HOB (D,E,F). Data are expressed as ng of mRNA per average ng of housekeeping mRNAs ± SD. Data are expressed as ng of mRNA per average ng of housekeeping mRNAs ± SD. *p < 0.05, **p < 0.001
