Table 4.

Multivariate survival analysis

Parameter	Disease-specific survival			Local recurrence-free survival			Metastasis-free survival
	HR	95% CI	P	HR	95% CI	P	HR	95% CI	P
Tumor regression grade	2.217	1.066-4.608	0.033*	2.933	1.316-6.536	0.009*	1.484	1.060-2.075	0.021*
SERPINB5 expression	2.792	1.105-7.058	0.030*	0.996	0.408-2.435	0.994	5.413	1.848-15.854	0.002*
Lymphovascular invasion	2.671	1.004-7.108	0.049*	4.097	1.337-12.551	0.014*	-	-	-
Pre-CCRT CEA	2.180	1.025-4.639	0.043*	2.653	1.090-6.028	0.031*
Post-CCRT T stage	1.963	0.814-4.734	0.133	1.635	0.650-4.109	0.296	1.700	0.747-3.873	0.206
Pre-CCRT N stage	-	-	-	1.581	0.653-3.827	0.310	-	-	-