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. 2018 Feb 28;9:319. doi: 10.3389/fmicb.2018.00319

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Copyright © 2018 Hansen and Atlung.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The three states of the DnaA protein. The thickness of the arrows indicate the approximate relative contributions of the different elements to the interconversion of the different forms. Stipled arrow: the relative contribution of phospholipid mediated nucleotide exchange (Sekimizu and Kornberg, 1988; Aranovich et al., 2006, 2015) is unknown. RIDA: Replicative inactivation of DnaA (Katayama et al., 1998; Kato and Katayama, 2001); DDAH: datA dependent ATP hydrolysis (Kasho and Katayama, 2013); DARS: DnaA Reactivating sequence (Fujimitsu et al., 2009).