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. 2018 Feb 28;9:326. doi: 10.3389/fmicb.2018.00326

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Copyright © 2018 Khalifa, Gelman, Shlezinger, Dessal, Coppenhagen-Glazer, Beyth and Hazan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Finding the most effective phage cocktail. (A) Logarithmic and (B) stationary phase E. faecalis V583 treated with EFDG1, EFLK1, and cocktails of these two phages in different ratios. Cocktail#1 (1:1), Cocktail#2 (1:2), Cocktail#3 (2:1), Cocktail#4 (1:3), and Cocktail#5 (3:1). Number of colony forming units per ml (CFU/ml) for logarithmic (C) and stationary phase (D) bacteria with and without treatment of the phages and their cocktails. (E) Biofilm biomass quantified by crystal violet staining of 2-weeks of E. faecalis V583 biofilm. (F) CFU/ml for phage treated and untreated 2-weeks old E. faecalis V583 biofilm.