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. 2018 Feb 28;9:333. doi: 10.3389/fimmu.2018.00333

Table 2.

Common transcripts induced under all six conditions (TNF, CT, LPS, each human and mouse data from Figure 2) and for which anti-inflammatory or tolerogenic functions have been reported.

Gene nameHuman/mouse, protein name Functions References for tolerogenicity
IL12B/IL12b
IL-12p40
p40 homodimer antagonizes IL-12p70 (29, 30)
IDO1/Ido1
Indoleamine-2,3-dioxigenase IDO
Metabolic inhibition of T cell proliferation by l-tryptophan catabolism (31, 32)
Cd150/SLAMF1/Slamf1
CD150/SLAM
Receptor for measles virus, inhibitor of DC function (3337)
INHBA/Inhba
Inhibin βA, Activin βA
Partially inhibits DC maturation. Synergizes with TGF-β for induction of Foxp3+ Tregs (38, 39)