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. 2018 Feb 15;10(2):455–464.

Figure 3.

Figure 3

Knockout of PLAC8 induces apoptosis and G2/M phase arrest in CNE2 cells. A: Detection of apoptosis by flow cytometry after Annexin V-FITC/propidium iodide (PI) staining of PLAC8(+) and PLAC8(-) cells at 48 h after irradiation at 0 or 6 Gy. B: The rate of apoptosis was significantly higher in IR-PLAC8(-) cells than PLAC8(+), PLAC8(-) and IR-PLAC8(+) cells. C: Cell cycle analysis of PLAC8(+) and PLAC8(-) cells at 48 h after irradiation at 0 or 6 Gy. D: The rate of G2/M cell cycle arrest was significantly higher in IR-PLAC8(-) cells than PLAC8(+), PLAC8(-) and IR-PLAC8(+) cells; All quantitative data shown represent the means ± SD of 3 independent replicates; significant differences were shown as **P < 0.01.