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. 2018 Feb 15;10(2):511–518.

Figure 3.

Figure 3

Re-expression of miR-384-5p in macrophages does not alter diabetic state of STZ-treated mice. Four group of mice of 10 of each were included in this experiment. Group 1, the mice received saline only injection (CTL). Group 2, mice received STZ only (STZ). Group 3, mice received STZ and AAV-null (STZ+AAV-null). Group 4, mice received STZ and AAV-miR-384-5p (STZ+AAV-miR-384-5p). All AAVs used CD68 promoter. Mice were followed for 6 weeks. A. Fasting blood glucose. B. Serum insulin. C. Immunostaining for insulin. D. Beta cell mass. *p<0.05. NS: non-significant. N=10. Scale bars are 100 μm.