Table III.
Distribution of PRR4 gene expression and its association with clinicopathological characteristics of the patients.
| PRR4 gene expression, n (%) | ||||
|---|---|---|---|---|
| Clinicopathological parameter | Decreased | No change | Increased | P-valuea |
| Clinical stage | 0.903 | |||
| Early stage (I+II) | 7 (7.8) | 0 (0) | 3 (3.3) | |
| Advanced stage (III+IV) | 57 (63.3) | 1 (1.1) | 20 (22.2) | |
| Unknown | 1 (1.1) | 0 (0) | 1 (1.1) | NT |
| Histology | NT | |||
| SCC | 64 (71.1) | 1 (1.1) | 21 (23.3) | |
| Non-SCC | 0 (0) | 0 (0) | 2 (2.2) | |
| Unknown | 1 (1.1) | 0 (0) | 1 (1.1) | |
| Sex | 0.951 | |||
| Female | 2 (2.2) | 0 (0) | 1 (1.1) | |
| Male | 63 (70) | 1 (1.1) | 23 (25.6) | |
| Age | 0.5 | |||
| ≤50 | 8 (8.9) | 0 (0) | 5 (5.6) | |
| >50 | 57 (63.3) | 1 (1.1) | 18 (20) | |
| Unknown | 0 (0) | 0 (0) | 1 (1.1) | NT |
| Histological grade | 0.327 | |||
| Low grade (1+2) | 31 (34.4) | 0 (0) | 8 (8.9) | |
| High grade (3+4) | 30 (33.3) | 1 (1.1) | 14 (15.6) | |
| Unknown | 4 (4.4) | 0 (0) | 2 (2.2) | NT |
| Smoking | 0.815 | |||
| Smoker | 53 (58.9) | 1 (1.1) | 20 (22.2) | |
| Non-smoker | 11 (12.2) | 0 (0) | 3 (3.3) | |
| Unknown | 1 (1.1) | 0 (0) | 1 (1.1) | NT |
| Total | 65 (72.2) | 1 (1.1) | 24 (26.7) | 0.001 |
a
Statistical analyses were performed using the Pearson's χ2 test. NT, not tested; SCC, squamous cell carcinoma; PRR4, proline-rich 4.