Table II.

Sensitivity and specificity of PAX1 and LMX1A for distinguishing CSCC from HSIL, LSIL and NC (CSCC vs. HSIL+LSIL+NC).

Gene	Cut-off	AUC	Sensitivity, %	Specificity, %	P-value	OR (95% CI)
PAX1	11.78	0.790	0.837	0.809	<0.001	0.788–0.923
LMX1A	7.185	0.633	0.357	0.893	0.029	0.508–0.758

CSCC, cervical squamous-cell carcinoma; HSIL, high-grade squamous intraepithelial lesion; NC, normal cervix; LSIL, low grade squamous intraepithelial lesion; AUC, area under the curve; OR, odds ratio; CI, confidence interval; PAX1, paired box gene 1; LMX1A, LIM homeobox transcription factor 1 α.