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. 2018 Jan 29;15(4):4649–4656. doi: 10.3892/ol.2018.7897

Figure 3.

Figure 3.

Effect of celecoxib on the expression of proteins associated with chemotherapy sensitivity in Jurkat and Hut-78 cells. (A) Reverse transcription quantitative polymerase chain reaction assays of the expression levels of P65, MDR1, MRP1, Bcl-2 and Bax mRNAs in Jurkat and Hut-78 cells. (B) Western blotting assays of the expression levels of P65, P-gp, encoded by MDR1, MRP1, Bcl-2 and BaX protein expression in Jurkat and Hut-78 cells. β-actin was used as an internal loading control. The experiments presented are representative of three independent experiments. *P<0.05 and **P<0.01 vs. the control group. P65, tumor protein 65; P-gp, P-glycoprotein; MDR1, multidrug resistance protein 1; MRP1, multidrug resistance-associated protein 1; Bcl-2, B-cell lymphoma 2, Bax, Bcl-2-associated X protein.