Effect of age on PLA2 and sPLA2 activity. The ages of all 330 patients included in the present study were obtained (169 patients with BC, 80 patients with BD and 81 healthy controls). An age of 50 years was used as a standard to assess the age distribution among the three groups due to menopausal status. No significant differences in PLA2 and sPLA2 activities were found using one way ANOVA. PLA2, phospholipase A2; sPLA2, secretory phospholipase A2; BC, breast cancer; BD, benign disease (P<0.05 was considered to indicate a statistically significant difference).