Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Feb 28;11:64. doi: 10.3389/fnmol.2018.00064

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Perez Carrion, Pischedda, Biosa, Russo, Straniero, Civiero, Guida, Gloeckner, Ticozzi, Tiloca, Mariani, Pezzoli, Duga, Pichler, Pan, Landers, Greggio, Hess, Goldwurm and Piccoli.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Mitochondrial fission upon MPP+ is impaired in E193K fibroblasts. (A) Primary fibroblasts obtained from healthy individuals and an E193K carrier were transfected with GFP or GFP-DRP1, treated with 1 mM MPP+ for 24 h and then incubated with MitotrackerRed to investigate mitochondrial morphology. Scale bars = 10 μm. (B,C) The graphs report mitochondrial interconnectivity (B) and content (C). Data are expressed as mean ± SE (n = 4, 5–6 cells/experiment); °°p < 0.01 vs. control treatment, same transfection, ***,°°°p < 0.001 vs. control treatment, same transfection, ^#p < 0.05 vs. GFP MPP+.