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Systemic toxicity of STP-NG/SHK against 143B osteosarcoma-bearing mice. (A) Weight changes. (B) Survival rates. (C) Mouse organs stained with H&E. Myocardia from mice in the SHK were damaged (★). No overt tissue damage was observed in STP-NG/SHK-treated mice. Scale bar = 100 μm (C). Each set of data is represented as mean ± SEM (for A, n = 7; *P < 0.05, #P < 0.01, &P < 0.001).
