Figure 2.

Next gene sequencing-based single nucleotide polymorphism haplotyping for embryos 7, 9 and 10. Gray and blue represent pathogenic and normal haplotype of the mother, respectively. Pink and dark orange represented pathogenic and normal haplotype of the father, respectively. Embryo 7 was genotypically normal and embryo 9 was affected. Paternal recombination occurred in embryo 10 (marked in purple). Allele drop-out sites are marked in yellow and gene mutation sites are marked in red.