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Plasma oxylipin levels in WT or Ephx-deficient mice. A, plasma levels of AA-derived epoxides and diols in WT, Ephx1−/−, Ephx2−/−, and Ephx1−/−Ephx2−/− mice. B, plasma levels of docosahexaenoic-, eicosapentaenoic-, and linoleic acid–derived epoxides and diols in WT, Ephx1−/−, Ephx2−/−, and Ephx1−/−Ephx2−/− mice; n = 9–11 per group. *, p < 0.05 versus WT; #, p < 0.05 versus Ephx2−/−. Results are expressed as mean ± S.E.
