Table 2.
MRI, EEG, brain 18F-FDG-PET, and CSF tau results/values of patients with sporadic Creutzfeldt-Jakob disease in 2015
| Patient ID | MRI | EEG | Brain 18F-FDG-PET | CSF tau, pg/mL | 
|---|---|---|---|---|
| #1 | FLAIR/DWI hyperintense right frontal cortex, bilateral gyri cinguli, bilateral caudate nuclei, and right anterior putamen; performed twice in 20 days; clear progression | Typical (PSWC) | Hypometabolism in right frontal and posterior parietal cortices as well as the cerebellum; hypermetabolism in basal ganglia | 2,280 | 
| #2 | FLAIR/DWI hyperintense right frontal operculum and right insular cortex; performed twice in 26 days; clear progression | Typical (PSWC) | Hypometabolism in cortex of right hemisphere and right basal ganglia | 2,500 | 
| #3 | FLAIR/DWI hyperintense left caudate nucleus, putamen, insular cortex, left frontal operculum, and bilateral limbic cortices; performed twice in 8 days; no progression | Typical (PSWC) | Hypometabolism in left parietal and frontal cortices and left putamen | 2,270 | 
| #4a | FLAIR/DWI hyperintense caudate nuclei, putamina, thalami, and limbic cortices bilaterally; performed twice in 23 days; clear progression | Not typical (progressive encephalopathy with slow activity) | Pronounced hypometabolism in basal ganglia bilaterally and cortex of the left hemisphere | 2,280 | 
| #5 | FLAIR/DWI hyperintense caudate nucleus, putamen, and thalamus; cortical ribboning | Typical (PSWC) | N/A | 2,270 | 
| #6 | FLAIR/DWI hyperintense bilateral caudate nuclei, putamina, cingulate gyri, and insular cortices; right temporal, frontal in the parietal cortex | N/A | N/A | N/A | 
| #7 | FLAIR/DWI asymmetrical hyperintense bilateral temporal, frontal, occipital, and parietal cortices, cingulate gyri bilaterally, and caudate nuclei bilaterally; putamina less evident; performed twice, clear progression | N/A | N/A | N/A | 
| #8 | N/A | N/A | N/A | N/A | 
| #9 | DWI hyperintense bilateral temporal cortices and right parietal cortex; no FLAIR changes | N/A | N/A | N/A | 
CSF, cerebrospinal fluid; N/A, not available; FLAIR, fluid-attenuated inversion recovery; DWI, diffusion-weighted imaging; PSWC, periodic sharp wave complexes.
Patient died in 2016, not included in the 2015 incidence.