Skip to main content
. 2018 Feb 8;8(1):42–50. doi: 10.1159/000486712

Table 2.

MRI, EEG, brain 18F-FDG-PET, and CSF tau results/values of patients with sporadic Creutzfeldt-Jakob disease in 2015

Patient ID MRI EEG Brain 18F-FDG-PET CSF tau, pg/mL
#1 FLAIR/DWI hyperintense right frontal cortex, bilateral gyri cinguli, bilateral caudate nuclei, and right anterior putamen; performed twice in 20 days; clear progression Typical (PSWC) Hypometabolism in right frontal and posterior parietal cortices as well as the cerebellum; hypermetabolism in basal ganglia 2,280

#2 FLAIR/DWI hyperintense right frontal operculum and right insular cortex; performed twice in 26 days; clear progression Typical (PSWC) Hypometabolism in cortex of right hemisphere and right basal ganglia 2,500

#3 FLAIR/DWI hyperintense left caudate nucleus, putamen, insular cortex, left frontal operculum, and bilateral limbic cortices; performed twice in 8 days; no progression Typical (PSWC) Hypometabolism in left parietal and frontal cortices and left putamen 2,270

#4a FLAIR/DWI hyperintense caudate nuclei, putamina, thalami, and limbic cortices bilaterally; performed twice in 23 days; clear progression Not typical (progressive encephalopathy with slow activity) Pronounced hypometabolism in basal ganglia bilaterally and cortex of the left hemisphere 2,280

#5 FLAIR/DWI hyperintense caudate nucleus, putamen, and thalamus; cortical ribboning Typical (PSWC) N/A 2,270

#6 FLAIR/DWI hyperintense bilateral caudate nuclei, putamina, cingulate gyri, and insular cortices; right temporal, frontal in the parietal cortex N/A N/A N/A

#7 FLAIR/DWI asymmetrical hyperintense bilateral temporal, frontal, occipital, and parietal cortices, cingulate gyri bilaterally, and caudate nuclei bilaterally; putamina less evident; performed twice, clear progression N/A N/A N/A

#8 N/A N/A N/A N/A

#9 DWI hyperintense bilateral temporal cortices and right parietal cortex; no FLAIR changes N/A N/A N/A

CSF, cerebrospinal fluid; N/A, not available; FLAIR, fluid-attenuated inversion recovery; DWI, diffusion-weighted imaging; PSWC, periodic sharp wave complexes.

a

Patient died in 2016, not included in the 2015 incidence.