Table 2.

Inflammasomes localized to the bladder urothelium and their potentially associated bladder pathologies

Inflammasome	Bladder condition(s) associated with inflammasome	Potential bladder condition(s) associated with inflammasome
NLRP1		UTI
NLRP3	cyclophosphamide-induced hemorrhagic cystitis BOO UTI bladder cancer
NLRP6		UTI bladder stone formation radiation cystitis bladder cancer interstitial cystitis
NLRP7		UTI
NLRP12		UTI interstitial cystitis
NLRC4	bladder cancer	UTI
AIM2		UTI

Seven inflammasomes in the NLR and AIM receptor family have been localized to the bladder urothelium. This table lists the known and potentially associated bladder inflammation diseases mediated by the inflammasomes.