Table 1.
Demographics and clinical characteristicsa
| Experiment 1 | Experiment 2 | |||||||
|---|---|---|---|---|---|---|---|---|
| FEP (n=23) | HV (n=23) | t/X2 | p value | HV (n=19) | t/X2 | p value | ||
| Gender (% male) | 69.6% | 69.6% | 0.00 | 1.0 | 63.2% | |||
| Age | 22.65 (1.03) | 22.65 (0.93) | 0.00 | 1.0 | 23.84 (3.67) | |||
| Parental Occupationb | 4.61 (4.62) | 3.78 (3.23) | −8.56 | .48 | 3.05 (3.66) | |||
| RBANSc | ||||||||
| Total index | 70.30 (16.11) | 92.62 (11.8) | 5.08 | <.01 | 97.79 (15.82) | |||
| Immediate memory | 80.05 (16.95) | 101.33 (14.20) | 4.37 | <.01 | 106.21 (16.45) | |||
| Visuospatial | 76.45 (17.13) | 85.76 (15.32) | 1.84 | .07 | 89.47 (16.63) | |||
| Language | 78.45 (13.41) | 98.81 (14.82) | 4.60 | <.01 | 103.47 (12.66) | |||
| Attention span | 72.90 (16.69) | 94.62 (17.24) | 4.10 | <.01 | 101.58 (16.35) | |||
| Delayed memory | 72.90 (20.84) | 93.19 (8.70) | 4.03 | <.01 | 91.32 (12.76) | |||
| BPRSd | Baseline | Ketaminee | ||||||
| Total score | 34.36 (11.91) | 20.84 (0.83) | 39.47 (6.97) | 11.12 | <.01 | |||
| Positive | 5.18 (2.82) | 3.00 (0.00) | 6.41 (1.54) | 9.11 | <.01 | |||
| Negative | 6.73 (2.96) | 3.32 (0.48) | 6.76 (2.51) | 6.03 | <.01 | |||
a
Mean (SD) unless indicated otherwise
b
Ranks determined from Diagnostic Interview for Genetic Studies (1 – 18 scale); higher rank (lower numerical value) corresponds to higher socioeconomic status
c
Repeatable Battery for the Assessment of Neuropsychological Status, FEP: n= 20; HC: n= 21
d
Brief Psychiatric Rating Scale (1 – 7 scale); positive (conceptual disorganization, hallucinatory behavior, and unusual thought content); negative (emotional withdrawal, motor retardation, and blunted affect), n= 22
e
n= 17