Table 2.
Preoperative and perioperative results in patients requiring and not requiring PPMI after TAVI with the LOTUS prosthesis
| With PPMI (15) | Without PPMI (51) | p-value | |
|---|---|---|---|
| Age (years) | 82.4 ± 5.7 | 79.9 ± 5.5 | 0.1 |
| Female gender | 46.7% | 60.8% | 0.3 |
| Body mass index | 27.1 ± 5.1 | 27.4 ± 4.1 | 0.8 |
| LVEF% | 57.0 ± 8.8 | 52.5 ± 15.0 | 0.2 |
| Atrial fibrillation | 26.7% | 19.6% | 0.4 |
| A-V block first degree | 20.0% | 6.0% | 0.1 |
| Right bundle branch block | 26.7% | 9.8% | 0.1 |
| Left bundle branch block | 6.7% | 21.6% | 0.1 |
| Logistic Euro-score | 5.0–49.7; 12.4 | 3.1–68.0; 14.0 | 0.5 |
| Euro-score II | 1.2–16.4; 3.4 | 1.6–27.9; 3.5 | 0.4 |
| STS-score | 1.0–9.1; 3.3 | 1.2–16.6; 3.7 | 0.4 |
| Annulus (mm) | 24.5 ± 1.4 | 24.1 ± 2.1 | 0.5 |
| LVOT (mm) | 24.2 ± 1.6 | 24.1 ± 2.3 | 0.9 |
| Bulbus aortae (mm) | 31.6 ± 3.1 | 30.5 ± 3.1 | 0.2 |
| Calcification vertical extension (mm)a | 9.4 ± 3.3 | 11.7 ± 4.4 | 0.2 |
| Operative time (min) | 60–180; 78 | 40–290; 80 | 0.4 |
| Radiation time (mm) | 14.5–64.7; 24 | 11.1–42.5; 21.6 | 0.1 |
| Group B | 20% | 55% | 0.02 |
| Valve retrieval | 20% | 2.2% | 0.04 |
| Valve full resheating | 13.3% | 13.0% | 0.1 |
| Prosthesis size (mm) | 25.5 ± 1.5 | 24.7 ± 1.5 | 0.09 |
| Prosthesis/annulus | 1.05 ± 0.05 | 1.02 ± 0.06 | 0.2 |
| Aortic valve area (cm2) | 1.7 ± 0.6 | 1.5 ± 0.3 | 0.1 |
| Mean gradient (mmHg) | 7.5 ± 2.8 | 7.8 ± 4.3 | 0.7 |
| Paravalvular leak (0–1–2) | 86.7%–13.3%–0 | 80.4%–19.6%–0 | 0.7 |
| In-hospital death | 6.7% | 3.9% | 0.5 |
| Hospitalization length (days) | 12.2 ± 8.5 | 8.1 ± 4.7 | 0.02 |
| Implantation depth mm (left coronary cusp) | 5.7 ± 1.8 | 3.4 ± 1.9 | < 0.0001 |
| Implantation depth mm (non-coronary cusp) | 3.5 ± 2.9 | 3.4 ± 2.1 | 0.9 |
LVOT, left ventricular outflow tract. Data are presented as absolute numbers, percentages, mean ± standard deviation for normally distributed variables and median with minimum and maximum values for variables with not-normal distribution
aFrom deepest point of calcification to highest point of calcification measured at pre-operative cardiac CT (nadir–zenith)