Fig.1.

Typical Clinicopathologic features of anti-HMGCR Myopathy. (A) Summary of clinical findings on exam and ancillary testing. (B) muscle MRI of the lower extremities. Note selective involvement of paraspinal, gluteals in the hip and posterior and medial compartments of the thigh. Short tau inversion recovery (STIR) signal increase can be patchy and asymmetric. (C) A typical hematoxylin and eosin stain of a patient with anti-HMGCR myopathy showing myofiber atrophy, degeneration, and regeneration without prominent lymphocytic inflammation.