Table 2.
Cox’s proportional hazard regression analysis of risk factors for overall survival in relapse patients
| Risk factor | N | Reference group | HR |
|---|---|---|---|
| CIMP (−/+) | (42/95) | CIMP+ | 1.81 (1.04–3.16) (*p = 0.036) |
| Sex (male/female) | (79/58) | Sex = female | 0.95 (0.56–1.60) |
| Age at primary diagnosis (years) | (137) | 1.04 (0.97–1.10) | |
| Initial risk group at primary diagnosis (SR/IR and HR) | (87/50) | Risk group = SR/IR | 0.96 (0.53–1.76) |
| HSCT after relapse (no/yes) | (79/58) | HSCT = no | 0.55 (0.32–0.97) (*p = 0.040) |
| IntReALL risk class (relapse site/time to relapse (SR/HR)) | (88/49) | Risk group = SR | 3.79 (1.98–7.29) (*p < 0.001) |