Table 4.
Minimally adjusted associations between nocturnal systolic blood pressure dipping percent and hypothesized predictors in obese middle-aged/older adults with prediabetes (A) without prediabetes (B).
| A. Prediabetes
| ||
|---|---|---|
| Predictor | B (SE) | p-value |
| HbA1c (%) | 6.24 (2.6) | 0.02* |
| C-reactive Protein (mg/L) | 0.57 (0.2) | 0.01* |
| Carotid-femoral PWV (m/sec) | 0.14 (0.4) | 0.74 |
|
| ||
|
Model R2=0.22 p=0.009* |
||
| B. No Prediabetes
| ||
|---|---|---|
| Predictor | B (SE) | p-value |
| HbA1c (%) | 0.43 (4.5) | 0.93 |
| C-reactive Protein (mg/L) | 0.00 (0.4) | 0.99 |
| Carotid-femoral PWV (m/sec) | −0.37 (0.7) | 0.58 |
|
| ||
|
Model R2=0.01 P=0.95 |
||
| C. Multivariable adjusted associations between hypothesized predictors and nocturnal systolic blood pressure dipping percent in middle-aged/older adults with prediabetes
| ||
|---|---|---|
| Predictor | B (SE) | p-value |
| HbA1c (%) | 7.59 (2.8) | 0.01* |
| C-reactive Protein (mg/L) | 0.58 (0.2) | 0.02* |
| Age (yrs) | −0.04 (0.01) | 0.79 |
| Sex (male) | −1.07 (2.2) | 0.64 |
| Body mass index (kg/m2) | 0.03 (0.2) | 0.89 |
| Average 24-hr systolic BP (mmHg) | −0.03 (0.07) | 0.67 |
| Lipid-lowering medication treatment (yes/no) | −1.76 (2.2) | 0.42 |
| Antihypertension medication treatment (yes/no) | 0.38 (2.0) | 0.85 |
|
Model R2=0.27 p=0.03* |
||
B: unstandardized regression coefficient; PWV: pulse wave velocity.
*
P<0.05 variable or model significantly associated with nocturnal systolic blood pressure dipping percent.