Table 3.

Univariate and multivariate analysis of candidate predictors of Gleason upgrade

Variables	Univariate		Multivariate
	OR (95% CI)	P Value	OR (95% CI)	P Value
Age	0.986 (0.942, 1.032)	.539	0.975 (0.922, 1.030)	.363
Race	1.004 (0.461, 2.185)	.993	0.790 (0.323, 1.935)	.606
Prebiopsy PSA (ng/mL)	1.097 (1.005, 1.198)	.037*	1.157 (1.039, 1.290)	.008*
Prostate volume (mL)	0.995 (0.980, 1.010)	.492	0.993 (0.966, 1.022)	.639
Clinical stage (cT2 vs cT1)	0.393 (0.150, 1.029)	.057	0.322 (0.109, 0.949)	.040*
Number of biopsy cores (saturation vs 12-core)	0.784 (0.407, 1.512)	.468	0.760 (0.340, 1.700)	.505
No. of positive cores	1.144 (0.997, 1.313)	.055	1.100 (0.915, 1.322)	.313
Max cancer % of cores	1.011 (1.000, 1.023)	.049*	1.009 (0.993, 1.025)	.270

OR, odds ratio; other abbreviations as in Tables 1 and 2.

^*P < .05 considered statistically significant.