. Author manuscript; available in PMC: 2019 Mar 1.

Published in final edited form as: Cell Microbiol. 2018 Jan 18;20(3):10.1111/cmi.12811. doi: 10.1111/cmi.12811

Table 2.

The 5 dominant canonical signaling pathways in hBMECs challenged with C. neoformans.

#	Pathway	Number of DEGs	Number of total genes	Ratio	P-value
1	Ephrin Receptor Signaling	20	174	0.115	5.17E-05
2	Axonal Guidance Signaling	36	433	0.083	1.01E-04
3	RhoGDI Signaling	19	173	0.11	1.45E-04
4	CXCR4 Signaling	17	152	0.112	2.56E-04
5	IL-8 Signaling	19	183	0.104	3.01E-04

The top canonical signaling pathways are mapped according to the ratios of differentially expressed genes (DEGs) to the total number of genes attributed to the pathway and the corresponding P-value.