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. 2018 Feb 28;51(2):98–103. doi: 10.5483/BMBRep.2018.51.2.222

Fig. 4.

Fig. 4

FOXM1 reduction was shown to decrease ABCG2 expression under DOX exposure. Two bladder cancer cells were transfected with siRNA (scRNA and siFOXM1) or overexpression vector (pcDNA and pFOXM1). After 24 h, transfected cells were exposed to 0.5 μM DOX for 24 h. mRNA (A) and protein (B, C) levels of FOXM1 and ABCG2 were analyzed by qPCR and western blotting methods.