Table 14:
Mean A1C Levels, Changes From Baseline With Continuous Glucose Monitoringa
| Study, Year | Intervention and Comparator | Mean A1C, Baseline (95% CI) | Mean A1C, End of Study (95% CI) | Change (95% CI) |
|---|---|---|---|---|
| Lind et al, 201731 | Standalone CGM plus multiple daily injections vs. SMBG plus multiple daily injections | 8.49 (8.41–8.57) | 7.92 (7.79–8.05) | −0.57 (−0.78 to −0.41) |
| Bergenstal et al, 201025 | Sensor-augmented pump vs. SMBG plus multiple daily injections | 8.30 (8.27–8.33) | 7.30 (7.25–7.35) | −1.00 (−1.08 to −0.92) |
| Quiros et al, 201541 | Sensor-augmented pump vs. SMBG plus insulin pump | 8.47 (8.33–8.61) | 7.38 (7.24–7.52) | −1.09 (−1.37 to −0.81) |
| Tumminia et al, 201538 | Standalone CGM plus insulin pump vs. SMBG plus insulin pump | 8.5 (8.38–8.62) | 7.82 (7.74–7.90) | −0.68 (−1.04 to −0.18) |
Abbreviations: CGM, continuous glucose monitoring; CI, confidence interval; SMBG, self-monitoring of blood glucose.
a
Note: Values used for deterministic analysis. Point estimates from Tumminia et al38 were not statistically or clinically meaningful.