Table 18:
Average Annual Per-Patient Cost of Diabetes Complications and Interventions in Ontario
| Mean Cost ($)a | Source | ||
|---|---|---|---|
| First Year | Subsequent Years | ||
| Health State: Diabetes-Related Complications | |||
| Nephropathy | 80 | 13 | O'Brien et al 200395 |
| Neuropathy | 192 | 192 | O'Brien et al 200395 |
| Retinopathy | 492 | 52 | O'Brien et al 200395 |
| Severe hypoglycemic event (in-patient visit) | 3,775 | 3,775 | McQueen et al, 201597 |
| Cardiovascular disease | 18,682 | 4,072 | O'Reilly et al, 200796 |
| Blindness | 3,483 | 2,482 | O'Reilly et al, 200796 |
| Lower-extremity amputation | 43,984 | 6,024 | O'Reilly et al, 200796 |
| End-stage renal disease | 28,221 | 12,808 | O'Reilly et al, 200796 |
| Intervention (Trade Name) | |||
| Sensor-augmented pump (Dexcom G4 Platinum + Animas Vibe) | 11,811 | 11,811 | Dexcom and Animasb |
| Sensor-augmented pump (Dexcom G5 Mobile + Animas Vibe) | 11,534 | 11,534 | Dexcom and Animasb |
| Sensor-augmented pump with a low-glucose suspend feature (MiniMed Veo) | 9,211 | 9,211 | Medtronicb |
| Standalone CGM plus multiple daily injections (Dexcom G4 Platinum) | 10,097 | 10,097 | Dexcomb |
| Standalone CGM plus multiple daily injections (Dexcom G5 Mobile) | 8,587 | 8,587 | Dexcomb |
| SMBG plus insulin pump (Animas Vibe or MiniMed Veo) | 6,817 | 6,817 | Medtronic and Animasb |
| SMBG plus multiple daily injections | 3,677 | 3,677 | Estimatec |
Abbreviations: CGM, continuous glucose monitoring; SMBG, self-monitoring of blood glucose.
a
We used 25% of the mean cost for calculations of standard error in our probabilistic sensitivity analysis. All costs are presented in 2017 Canadian dollars.
b
Manufacturer information.
c
See Appendix 6, Table A13, for more details.