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. Author manuscript; available in PMC: 2018 Mar 5.
Published in final edited form as: J Neuroimmune Pharmacol. 2011 Jun 14;6(4):585–596. doi: 10.1007/s11481-011-9284-5

FIGURE 1.

FIGURE 1

NT treatment induces 1L-1β expression in the brain. A: C57BL/6 mice were injected with single i.p. injection of 7.5 μg NT and, at various times following NT administration, the brain mRNA was analyzed by qPCR for IL-1β expression. B: Brain IL-1β qPCR analysis of LEW Rats injected with single i.p. injection of 62.5 μg NT at various time points after administration. C: C57BL/6 mice were chronically exposed to NT (2 mg/kg/day) through Alzet miniosmotic pumps, and brain tissues were analyzed by qPCR for 1L-1β expression at 2 days, 4 days and 8 days post NT treatment. D: qPCR analysis of IL-1β expression in the brain of LEW Rats chronically exposed to NT (2 mg/kg/day) 1-3 wk post NT treatment. Bar graphs represent mean ± SEM from 5rats/group. * P ≤ 0.05.