FIGURE 3.

Chronically NT-treated IL-1R KO mice have higher brain expression of IL-1β mRNA than WT C57BL/6 mice. Mice (IL-1R KO and WT) were treated with NT (1 mg/kg/day) via Alzet miniosmotic pumps, and brain tissues were analyzed for 1L-1β expression by qPCR after 3 wk of NT treatment. Bar graphs represents mean ± SEM from five mice/group, * P≤ 0.05.